I am doing a normalization and update of data on Microbiome Prescription. There are many items to review and items that have been reviewed have { } in their name. The pattern is:
- Scientific Name
- {Common Name}
- Other Information
and not reviewed (YET)
So far in this review, I have come across two substances (more likely to come) where there has been many or interesting studies for Autism
Sulforaphane
This is found in broccoli sprouts,cauliflower, kale, cole crops, cabbage, collards, mustard, and cress
- Sulforaphane Treatment in Children with Autism: A Prospective Randomized Double-Blind Study.
- Therapeutic efficacy of sulforaphane in autism spectrum disorders and its association with gut microbiota: animal model and human longitudinal studies
- Current understanding and future directions of cruciferous vegetables and their phytochemicals to combat neurological diseases.
- Exploring sulforaphane as neurotherapeutic: targeting Nrf2-Keap & Nf-Kb pathway crosstalk in ASD.
- A Review on Autism Spectrum Disorder: Pathogenesis, Biomarkers, Pharmacological and Non-Pharmacological Interventions.
- Emerging drugs for the treatment of irritability associated with autism spectrum disorder.
Zinc
- Dietary zinc supplementation rescues fear-based learning and synaptic function in the Tbr1(+/-) mouse model of autism spectrum disorders.
- Potential importance of supplementation with zinc for autism spectrum disorder.
- The Assessment of Selenium, Aluminum, and Zinc in Children with Autism Spectrum Disorder.
- Differential effectiveness of dietary zinc supplementation with autism-related behaviours in Shank2 knockout mice.
- Zinc Water Prevents Autism-Like Behaviors in the BTBR Mice.
- xploring potential mechanisms for zinc deficiency to impact in autism spectrum disorder: a narrative review.
- Zinc deficiency and supplementation in autism spectrum disorder and Phelan-McDermid syndrome.
- Zinc Status and Autism Spectrum Disorder in Children and Adolescents: A Systematic Review.
- The association of vitamin A, zinc and copper levels with clinical symptoms in children with autism spectrum disorders in Jilin Province, China.
- Neurodevelopmental Consequences of Dietary Zinc Deficiency: A Status Report.
- The Role of Zinc and NMDA Receptors in Autism Spectrum Disorders.
- Zinc is a key regulator of gastrointestinal development, microbiota composition and inflammation with relevance for autism spectrum disorders.
- Impact of Zinc Oxide Nanoparticles on the Composition of Gut Microbiota in Healthy and Autism Spectrum Disorder Children.
- The role of zinc supplementation on the metallothionein system in children with autism spectrum disorder.
- In vitro zinc supplementation alters synaptic deficits caused by autism spectrum disorder-associated Shank2 point mutations in hippocampal neurons.
- Dietary Zinc Supplementation Prevents Autism Related Behaviors and Striatal Synaptic Dysfunction in Shank3 Exon 13-16 Mutant Mice.
and more studies…
Glyphosate
Studies from US National Library of Medicine
“Furthermore, it has been reported that most infant formulas are contaminated with glyphosate. One study reported levels between 0.03 mg kg−1 and 1.08 mg kg−1. This could potentially further exacerbate the problem of Bifidobacterium reduction in the infant gut.” This may be a factor for increasing Autism and ADHD rates.
Impact of glyphosate (RoundupTM) on the composition and functionality of the gut microbiome
- Is autism a PIN1 deficiency syndrome? A proposed etiological role for glyphosate.
- Maternal exposure of mice to glyphosate induces depression- and anxiety-like behavior in the offspring via alterations of the gut-brain axis.
- Autism-like Behaviors in Male Juvenile Offspring after Maternal Glyphosate Exposure.
- Pesticides used in Europe and autism spectrum disorder risk: can novel exposure hypotheses be formulated beyond organophosphates, organochlorines, pyrethroids and carbamates? – A systematic review.
- The relationship between pesticide exposure during critical neurodevelopment and autism spectrum disorder: A narrative review.
- Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase.
- Gut microbiota and neurological effects of glyphosate.
- Inflammatory state and autism-like behavioral phenotype of offspring induced by maternal exposure to low-dose chemical mixtures during pregnancy in mice.
- Clostridium Bacteria and Autism Spectrum Conditions: A Systematic Review and Hypothetical Contribution of Environmental Glyphosate Levels.
- Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup).
- Elevated Urinary Glyphosate and Clostridia Metabolites With Altered Dopamine Metabolism in Triplets With Autistic Spectrum Disorder or Suspected Seizure Disorder: A Case Study.