A reader passed me a link to an article published on May 23, 2020 which was very interesting.
Dysbiosis of Gut Fungal Microbiota in Children With Autism Spectrum Disorders, J Autism Dev Disorders , 2020 May 23. doi: 10.1007/s10803-020-04543-y.
” Among the 507 genera identified, Saccharomyces and Aspergillus showed significant differences between ASD (59.07%) and Control (40.36%), indicating that they may be involved in the abnormal gut fungal community structure of ASD. When analyzed at the species level, a decreased abundance in Aspergillus versicolor was observed while Saccharomyces cerevisiae was increased in children with ASD relative to controls. “
The implication are simple:
- Do not supplement with any Saccharomyces probiotics. Check carefully any probiotics that you use to insure there is none
- Supplement with Aspergillus probiotics. There is one that I know of (and use). It is from Japan and called Strong Wakamoto. It consists of:
I have been in recent discussion with a Ph.D. researching aspergillus oryzae because it frees up a lot of nutrients in food. There are over 3000 studies citing aspergillus, for example:
Production of GABA-enriched idli with ACE inhibitory and antioxidant properties using Aspergillus oryzae: the antihypertensive effects in spontaneously hypertensive rats.
A combination of acid lactase from Aspergillus oryzae and yogurt bacteria improves lactose digestion in lactose maldigesters synergistically: A randomized, controlled, double-blind cross-over trial.
This is based on a report of a distinctive shift. Conceptually, Wakamoto would complete with Saccharomyces, reducing their numbers and altering the microbiome. There are no clinical studies done. Wakamoto is deemed safe and has been in use for a very long time in Japan.
2 thoughts on “Gut Fungal and Autism”
Hi Ken, my little boy was doing really well once we got rid of his cdiff and his doctor prescribed sacc B afterwards. he has been on a sliding scale downwards since and developed extremely high levels of prevotella copri. he immediately starting OCD behaviours and in his own world and I was told to persist with the sacc boulardi because it was likely die off fungal (which i did for a few weeks) but I’m sure it gave him fungal issues instead. He really hasn’t;t been doing well despite my efforts to lower his copri. Do you think its plausible that the sacc boulradi added to his fungal load and therefore also fed his copri? is a sacc boulardi fungal load treated like any other fungus ie caprylic acid etc. Does this product help to reduce sacc boulardi species?
Looking at https://microbiomeprescription.com/library/details?taxon=165179
we find that saccharomyces boulardii (probiotics) DOES INCREASE prevotella copri in some studies. In other studies, it decreases… so it is a risky treatment
To reduce P.C. see the same page